Having issues with high processor utilization or :
•It takes a long time to open applications
•High network bandwidth usage occurs
•Programs like Microsoft Word, Excel, and Outlook slow down
Then the following article from Trend may help
http://esupport.trendmicro.com/support/viewxml.do?ContentID=EN-1034528&id=EN-1034528
It involves the installation of a hot fix.
CIAOPS 